Methyl Detox Profile
Why get profiled?
The Methyl Detox Profile tests critical genes in the methylation pathway. The methylation pathway is the major part of detoxification and the metabolic cycle. More than 50% of people are affected by genetic variations in the methylation pathway 1-3. This profile enables you to intelligently use nutritional supplementation based on your genetics. The Methyl Detox Profile gives comprehensive insights into the functional status of 3 major genes associated with the methionine/homocysteine cycle. A Methyl Detox Profile may benefit you if you are experiencing any of the following:
Cardiovascular Diseases
Musculoskeletal Disorders
Neurological Disorders
Eye Diseases
Metabolic Conditions
Cancer
Methyl Detox Profile Pricing & Contents
Advanced 2 (Genetic Only)
$329
MTHFR
MTR
MTRR
COMT
AHCY
30-minute review of results
Homocysteine
The responsibility for blood draw services rests with the individual purchasing the test, and the pricing does not include any fees that a third party may charge. We do not handle the scheduling of blood draws. Upon receiving your test kit, you will find a prepaid mailing envelope included for convenient shipment of your sample to the lab.
For the Methyl Detox Test, you have the option of a blood draw or saliva swab. However, please note that a blood draw is always necessary for the Homocysteine test.
When ordering your test, please email your date of birth and indicate whether you prefer a saliva or blood draw kit to pronutritiondietitian@gmail.com.
Test Components
MTHFR
The MTHFR gene’s purpose is to produce the important MTHFR enzyme in the body. This enzyme is an important part of maintaining optimal health. If the MTHFR gene has a mutation, folate metabolism can be negatively impacted. Improper folate metabolism is implicated in many different diseases.
MTRR
The MTRR gene codes for the important enzyme, methionine synthase reductase (MSR). Methionine synthase reductase is required for the proper function of methionine synthase (see MTR). Both genes act together to convert homocysteine to methionine. Mutations can be involved with the development of cancers, Parkinson’s disease, depression, hypertension and many others.
AHCY
AHCY is the only enzyme known to convert S-Adenosylhomocysteine (AdoHcy) to homocysteine. It is crucial that AHCY immediately converts AdoHcy to homocysteine and adenine in order to maintain optimal methylation potential. Studies show a link between mutations in this gene with poor methylation potential and severe myopathies, developmental delays and hypermethioninemia.
MTR
MTR codes for the enzyme, methionine synthase (MS). MS converts homocysteine to methionine using methylated vitamin B12. Mutations in this gene significantly impact homocysteine metabolism, which can increase the risk for a number of chronic conditions such as cardiovascular diseases, metabolic and neurological conditions and certain cancers.
COMT
COMT is the major gene involved in methylation. It plays an important role in a variety of disorders, including estrogen-induced cancers, Parkinson’s disease, depression, hypertension and many others. COMT is also necessary for maintaining the proper balance of neurotransmitters with SAMe obtained from methionine. Genetic mutations in COMT can result in various neurological problems and has also been associated with Autism.
Homocysteine
Homocysteine is an amino acid that is involved in maintaining the methionine cycle. Elevated homocysteine levels are well-known risk factors for chronic disease, particularly cardiovascular, diabetes and neurodegenerative disorders.
When purchasing your test expect the following:
The kit will be shipped containing the necessary supplies within 4-7 business days.
See what people are saying
Helen has really helped me understand how to fuel my body correctly. No food or food groups are off-limits. She teaches you how to read food labels and how to combine foods to make a balanced plate so that you feel satisfied. What I love about Helen the most is how positive and encouraging she is! I never feel judged, just empowered to continue on my journey.
As someone who has never been extremely fit or healthy, it took a couple of health diagnoses for me to decide to change my unhealthy habits. My weight had crept up over time and I was technically considered obese. I decided it was finally time to prioritize my health.
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I HIGHLY recommend Helen Agresti. Within the past month, she’s helped me lose 11 lbs. without having to resort to any fad diet. I’ve been going back and forth with keto for years… I can eat bread now. I’ve had no cravings at all because I’m eating a balanced diet. She’s taught me how to read labels and cut chemicals out of my food. I could go on and on, but I feel so much better and healthier. The money I saved on groceries alone over the past month has already paid for the initial consult. I cannot recommend her enough.
Helen has completely changed the way I look at nutrition and a healthy lifestyle. She has taught me the balance of giving my body what it needs, while also enjoying life at the same time. Helen helped me find a workout routine that works best for me and was sustainable. I am forever grateful for her support and motivation to get me on the right track to feeling my absolute best!
I am so grateful to find Helen. She has help me understand nutrition and how to fuel my body so I don’t feel deprived. She has helped me to understand my portions of food, and given me guidance to understand the value in good wholesome foods. I am down 25 pounds and feeling great! I am so happy to be headed in the right direction.
I am so happy I decided to change my life and schedule an appointment with Helen. She has truly helped change my whole mindset. She’s taught me to stick to better sleep, and an eating schedule to get my metabolism running. With just a few tweaks to my schedule and enjoying eating my food instead of skipping meals, I’ve boosted my metabolism and lost 19lbs in 1 month! I’m so grateful to Helen and excited I finally found a lifestyle change that will last forever.
As soon as I met Helen I knew I made a life-changing choice. I have been struggling with losing a few pounds and trying to figure out what to eat for optimal health benefits. From my first visit, I knew I was on my way to a healthier me. Helen has educated me in several areas. Most importantly, learning how to fuel my body nutritiously. She also introduced me to an exercise program that fits my fitness level.
I recently began using Helen’s app that helps with meal planning. Helen created a nutrition prescription for me and the app gives menu options for breakfast, snacks, lunch and dinner. These are healthy choices that are easy and delicious. If there is something on the menu I do not find appealing, I am able to swap out the meal for other options. This app makes it easy to try new and different combinations of energizing food.
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